[{"id":88,"date":"2024-05-29T14:29:53","date_gmt":"2024-05-29T14:29:53","guid":{"rendered":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/?page_id=88"},"modified":"2024-05-29T15:52:02","modified_gmt":"2024-05-29T15:52:02","slug":"key-figures","status":"publish","type":"page","link":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/key-figures\/","title":{"rendered":"The Story In Pictures"},"content":{"rendered":"\n<p>Below are some prominent figures from the Saldanha Lab&#8217;s publications over the past 20 years. <\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1146\" height=\"468\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-29-at-11.50.16-AM.png\" alt=\"\" class=\"wp-image-99\" style=\"width:619px;height:auto\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-29-at-11.50.16-AM.png 1146w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-29-at-11.50.16-AM-300x123.png 300w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-29-at-11.50.16-AM-1024x418.png 1024w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-29-at-11.50.16-AM-768x314.png 768w\" sizes=\"(max-width: 1146px) 100vw, 1146px\" \/><figcaption class=\"wp-element-caption\"><strong><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/neu.20147\">Saldanha et al., 2005<\/a><\/strong> Two tags were used in this immunocytochemistry experiment. One tag was specific to aromatase (red) and one tag was specific to glial cells (green). The image above shows the red and green tagged images superimposed on each other, and the yellow is where the two overlap. All red areas contain some yellow, while there are some green areas that do not. This indicates that all aromatase-expressing cells are glial but not all glial cells express aromatase.<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"413\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha2022-1024x413.jpeg\" alt=\"\" class=\"wp-image-97\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha2022-1024x413.jpeg 1024w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha2022-300x121.jpeg 300w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha2022-768x310.jpeg 768w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha2022-1536x620.jpeg 1536w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha2022-2048x827.jpeg 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\"><strong><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jne.13192\">Saldanha 2022<\/a><\/strong> Pseudo-colored, contrast-enhanced, and sharpened photomicrographs depicting neuronal aromatase expression in pre- and post- synaptic boutons, as well as astroglia. Panel A depicts aromatase expression in neurons, B in terminals, and C in reactive astrocytes. <\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" width=\"520\" height=\"520\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha2011.jpeg\" alt=\"\" class=\"wp-image-92\" style=\"width:621px;height:auto\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha2011.jpeg 520w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha2011-300x300.jpeg 300w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha2011-150x150.jpeg 150w\" sizes=\"(max-width: 520px) 100vw, 520px\" \/><figcaption class=\"wp-element-caption\"><strong><a href=\"https:\/\/academic.oup.com\/edrv\/article\/32\/4\/532\/2354757\">Saldanha et al., 2011<\/a><\/strong> Panel A is a low-power, pseudocolored image of aromatase expression in various brain areas of the black capped chickadee. Panel B shows a high-power photomicrograph of aromatase expression in the preoptic neurons in the adult zebra finch brain (brown). Panel C indicates that aromatase has abundant expression in the cytoplasm of cell bodies, but not neuronal nuclei (n) in adult zebra finches. Panel C is a Immunoelectronmicrograph which shows a presynaptic bouton which innervates a dendrite expressing aromatase in an adult male zebra finch. <\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"914\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-24-at-1.56.10-PM-1-1024x914.png\" alt=\"\" class=\"wp-image-91\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-24-at-1.56.10-PM-1-1024x914.png 1024w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-24-at-1.56.10-PM-1-300x268.png 300w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-24-at-1.56.10-PM-1-768x685.png 768w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-24-at-1.56.10-PM-1.png 1264w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\"><strong><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0091302221000698?via%3Dihub\">Schlinger et al., 2022<\/a><\/strong> The light blue in these images shows aromatase expression in different brain areas of a male black-capped chickadee.\u00a0There is a distinct presence of aromatase in the hippocampus and caudomedial<br>nidopallium (NCM).<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1140\" height=\"838\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-29-at-9.53.26-AM.png\" alt=\"\" class=\"wp-image-94\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-29-at-9.53.26-AM.png 1140w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-29-at-9.53.26-AM-300x221.png 300w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-29-at-9.53.26-AM-1024x753.png 1024w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-29-at-9.53.26-AM-768x565.png 768w\" sizes=\"(max-width: 1140px) 100vw, 1140px\" \/><figcaption class=\"wp-element-caption\"><strong><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1559905\/\">Peterson et al., 2005<\/a><\/strong> This figure shows aromatase expression in the hypothalamic preoptic area (HPOA) (A), caudomedial nidopallium (NCM) (B), hypothalamus (HP) (C), and the high vocal center (HVC) (D). In panels A and B arrows indicate where aromatase immunoproduct is visible along tracts of the rough ER (RER) but not the nucleus (N) or nucleolus (Nu). Aromatase expression (indicated by arrows) can also be seen in the presynaptic terminals in panels C and D.\u00a0<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"775\" src=\"http:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/BaileySaldanha2015-1024x775.jpg\" alt=\"\" class=\"wp-image-81\" style=\"width:620px;height:auto\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/BaileySaldanha2015-1024x775.jpg 1024w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/BaileySaldanha2015-300x227.jpg 300w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/BaileySaldanha2015-768x581.jpg 768w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/BaileySaldanha2015-1536x1162.jpg 1536w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/BaileySaldanha2015-2048x1550.jpg 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\"><strong><a href=\"http:\/\/panel%20a%20shows%20the%20where%20the%20hippocampus%20(hp)%20is%20in%20the%20zebra%20finch%20brain.%20panel%20b%20shows%20where%20the%20caudomedial%20nidopallium%20(ncm)%20is%20in%20the%20zebra%20finch%20brain.%20panels%20a%20and%20b%20are%20to%20help%20the%20viewer%20orient%20panels%20c%20and%20d%20in%20the%20brain.%20panel%20c%20shows%20aromatase%20mrna%20expression%20in%20the%20hp%20and%20panel%20d%20shows%20aromatase%20mrna%20expression%20in%20the%20ncm.\/\">Bailey &amp; Saldanha, 2015<\/a><\/strong>\u00a0Panel A shows the where the hippocampus (HP) is in the zebra finch brain. Panel B shows where the caudomedial nidopallium (NCM) is in the zebra finch brain. Panel C shows aromatase mRNA expression in the HP and panel D shows aromatase mRNA expression in the NCM.\u00a0It can be seen that there is an abundance of aromatase mRNA expression, indicating the role of E2 in both spatial memory and auditory discrimination, respectively.<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"356\" src=\"http:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/DuncanSaldanha2020-1024x356.jpg\" alt=\"\" class=\"wp-image-82\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/DuncanSaldanha2020-1024x356.jpg 1024w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/DuncanSaldanha2020-300x104.jpg 300w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/DuncanSaldanha2020-768x267.jpg 768w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/DuncanSaldanha2020-1536x534.jpg 1536w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/DuncanSaldanha2020-2048x713.jpg 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\"><strong><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0091302219300810?via%3Dihub\">Duncan &amp; Saldanha, 2020<\/a><\/strong>\u00a0In this experiment, the zebra finch brain was mildly concussed over several days. The image on left shows where on the zebra finch brain injuries were applied. The image on the right shows the upregulation of glial aromatase (purple) due to the injuries. There is a noticeable increase in aromatase expressing glial cells around the injury site.\u00a0<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"850\" height=\"687\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Bailey2013-1.jpeg\" alt=\"\" class=\"wp-image-95\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Bailey2013-1.jpeg 850w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Bailey2013-1-300x242.jpeg 300w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Bailey2013-1-768x621.jpeg 768w\" sizes=\"(max-width: 850px) 100vw, 850px\" \/><figcaption class=\"wp-element-caption\"><strong><a href=\"https:\/\/academic.oup.com\/endo\/article\/154\/12\/4707\/2433353?login=true\">Bailey et al., 2013<\/a><\/strong>\u00a0The average E2 concentration in plasma and different brain areas across treatment. ATD is an aromatase inhibitor, which is to say, it inhibits the synthesis of E2. SIL (silicone) is a control treatment. The plasma has the lowest concentration of E2 of all the measured areas. The Hippocampus (HP) has the highest E2 levels. ATD only significantly lowered E2 concentrations relative to SIL in the HP, not the caudomedial nidopallium (NCM) or diencephalon.<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"826\" src=\"http:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-24-at-1.22.04-PM-1-1024x826.png\" alt=\"\" class=\"wp-image-78\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-24-at-1.22.04-PM-1-1024x826.png 1024w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-24-at-1.22.04-PM-1-300x242.png 300w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-24-at-1.22.04-PM-1-768x620.png 768w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Screenshot-2024-05-24-at-1.22.04-PM-1.png 1242w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\"><strong><a href=\"https:\/\/academic.oup.com\/endo\/article\/154\/12\/4707\/2433353?login=true\">Bailey et al., 2013<\/a><\/strong>\u00a0The above graph shows the mistakes birds made across treatment group in a spatial memory task. Birds in the ATD group received an ATD soaked pellet resting on their brain. Birds in the SIL group only received a silicone pellet on their brain (control). Birds in the LESION group received 0.1 \u03bcL of ibotenic acid in 0.1 M PBS injected into the HP. Birds in the SHAM group received only 0.1 \u03bcL of PBS injected into the HP (control). Birds in the CRANIOTOMY group remained under anesthesia for 5 minutes. Birds in both control groups, SIL and SHAM, had the lowest number of mistakes. There was no difference between SIL and SHAM birds. Birds in the ATD and LESION groups had the highest number of mistakes. There was no difference between ATD and LESION birds. This indicates that ATD has comparable effects to an entire hippocampal lesion.<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"908\" height=\"586\" src=\"http:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Wynne2007.png\" alt=\"\" class=\"wp-image-85\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Wynne2007.png 908w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Wynne2007-300x194.png 300w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Wynne2007-768x496.png 768w\" sizes=\"(max-width: 908px) 100vw, 908px\" \/><figcaption class=\"wp-element-caption\"><strong><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/glia.20594\">Wynne et al., 2007<\/a><\/strong>\u00a0Secondary degeneration refers to the damage that spreads from the primary site of injury over time, it peaks at 24 hours post injury.\u00a0The secondary wave of degeneration following brain injury is depicted here. In this experiment, the hemispheres of the birds\u2019 brain were severed and a shot of saline was injected into one side and a shot of fadrozole was injected into the other. Fadrozole is an aromatase inhibitor and saline is a control treatment. The birds were sacrificed at different time intervals and the second wave of degeneration was measured. The side injected with saline had no secondary wave of degeneration, whereas the side injected with fadrozole had a near perfect wave of secondary degeneration. This indicates the necessity of aromatase in injury.<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"766\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha20113-1024x766.jpeg\" alt=\"\" class=\"wp-image-96\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha20113-1024x766.jpeg 1024w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha20113-300x225.jpeg 300w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha20113-768x575.jpeg 768w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Saldanha20113.jpeg 1280w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\"><strong><a href=\"https:\/\/academic.oup.com\/edrv\/article\/32\/4\/532\/2354757\">Saldanha et al., 2011<\/a><\/strong> This cartoon illustrates the three different traditional forms of hormonal signaling. Endocrine signaling involves hormones being secreted into the vascular system and delivered to targets centimeters or meters away. Paracrine signaling involves hormones secreted into extracellular fluid and delivered to relatively close targets (typically in the same organ). Autocrine signaling involves a cell\u2019s own hormone signaling activating itself. Synaptocrine signaling is our hypothesis of an alternative type of hormonal signaling that involves the synthesis of hormones in presynaptic boutons. The synaptocrine theory defines a type of neuromodulation wherein estrogens are shown to have regulated presynaptic synthesis and postsynaptic actions. This shifts the perception of estrogen from only being considered as a peripheral signal (as in the endocrine system) to include signaling systems intrinsic to the brain (synapses).\u00a0<\/figcaption><\/figure>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/about-us-2\/\">About US<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/publications\/\">Selected Publications<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Below are some prominent figures from the Saldanha Lab&#8217;s publications over the past 20 years.<\/p>\n","protected":false},"author":4248,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-88","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages\/88","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/users\/4248"}],"replies":[{"embeddable":true,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/comments?post=88"}],"version-history":[{"count":0,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages\/88\/revisions"}],"wp:attachment":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/media?parent=88"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}},{"id":54,"date":"2024-05-17T18:35:51","date_gmt":"2024-05-17T18:35:51","guid":{"rendered":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/?page_id=54"},"modified":"2024-05-17T18:35:51","modified_gmt":"2024-05-17T18:35:51","slug":"publications","status":"publish","type":"page","link":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/publications\/","title":{"rendered":"Selected Publications"},"content":{"rendered":"\n<p>Saldanha CJ. (2023). Spatial and temporal specificity of neuroestradiol provision in the songbird. <em>J Neuroendocrinol.<\/em> 35(2):e13192. doi: <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jne.13192\">10.1111\/jne.13192<\/a>. Epub 2022 Aug 19.<\/p>\n\n\n\n<p>Schlinger BA, Remage-Healey L, Saldanha CJ. (2022). The form, function, and evolutionary significance of neural aromatization. <em>Front Neuroendocrinol.<\/em> 64. doi: <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0091302221000698\">10.1016\/j.yfrne.2021.100967<\/a><\/p>\n\n\n\n<p>Saldanha CJ. (2020). Estrogen as a Neuroprotectant in Both Sexes: Stories From the Bird Brain. <em>Front Neurol.<\/em> 11:497. doi: <a href=\"https:\/\/www.frontiersin.org\/journals\/neurology\/articles\/10.3389\/fneur.2020.00497\/full\">10.3389\/fneur.2020.00497.<\/a><\/p>\n\n\n\n<p>Pedersen AL, Brownrout JL, Saldanha CJ. (2018). Neuroinflammation and neurosteroidogenesis: Reciprocal modulation during injury to the adult zebra finch brain. <em>Physiol Behav.<\/em> 187:51-56. doi: <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0031938417303529?via%3Dihub\">10.1016\/j.physbeh.2017.10.013<\/a>. Epub 2017 Oct 13.<\/p>\n\n\n\n<p>Pedersen AL, Saldanha CJ. (2017). Reciprocal interactions between prostaglandin E2- and estradiol-dependent signaling pathways in the injured zebra finch brain. <em>J Neuroinflammation.<\/em> 14(1):262. doi: <a href=\"https:\/\/jneuroinflammation.biomedcentral.com\/articles\/10.1186\/s12974-017-1040-1\">10.1186\/s12974-017-1040-1.<\/a><\/p>\n\n\n\n<p>Cornil CA, Leung CH, Pletcher ER, Naranjo KC, Blauman SJ, Saldanha CJ. (2012). Acute and specific modulation of presynaptic aromatization in the vertebrate brain. <em>Endocrinology.<\/em> 153(6):2562-7. doi: <a href=\"https:\/\/academic.oup.com\/endo\/article\/153\/6\/2562\/2423781?login=true\">10.1210\/en.2011-2159<\/a>. Epub 2012 Apr 16.<\/p>\n\n\n\n<p>Saldanha CJ, Remage-Healey L, Schlinger BA. (2011). Synaptocrine signaling: steroid synthesis and action at the synapse. <em>Endocr Rev.<\/em> 32(4):532-49. doi: <a href=\"https:\/\/academic.oup.com\/edrv\/article\/32\/4\/532\/2354757?login=true\">10.1210\/er.2011-0004.<\/a> Epub 2011 May 26.<\/p>\n\n\n\n<p>Bailey DJ, Wade J, Saldanha CJ. (2009). Hippocampal lesions impair spatial memory performance, but not song&#8211;a developmental study of independent memory systems in the zebra finch. <em>Dev Neurobiol.<\/em> 69(8):491-504. doi: <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/dneu.20713\">10.1002\/dneu.20713<\/a>.<\/p>\n\n\n\n<p>Saldanha CJ, Tuerk MJ, Kim YH, Fernandes AO, Arnold AP, Schlinger BA. (2000). Distribution and regulation of telencephalic aromatase expression in the zebra finch revealed with a specific antibody. <em>J Comp Neurol<\/em>. 423(4):619-30. doi: <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/1096-9861(20000807)423:4%3C619::AID-CNE7%3E3.0.CO;2-U\">10.1002\/1096-9861(20000807)423:4&lt;619::aid-cne7&gt;3.0.co;2-u.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Saldanha CJ. (2023). Spatial and temporal specificity of neuroestradiol provision in the songbird. J Neuroendocrinol. 35(2):e13192. doi: 10.1111\/jne.13192. Epub 2022 Aug 19. Schlinger BA, Remage-Healey L, Saldanha CJ. (2022). The form, function, and evolutionary significance of neural aromatization. Front Neuroendocrinol. 64. doi: 10.1016\/j.yfrne.2021.100967 Saldanha CJ. (2020). Estrogen as a Neuroprotectant in Both Sexes: Stories From [&hellip;]<\/p>\n","protected":false},"author":4248,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-54","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages\/54","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/users\/4248"}],"replies":[{"embeddable":true,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/comments?post=54"}],"version-history":[{"count":0,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages\/54\/revisions"}],"wp:attachment":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/media?parent=54"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}},{"id":53,"date":"2024-05-17T18:35:51","date_gmt":"2024-05-17T18:35:51","guid":{"rendered":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/?page_id=53"},"modified":"2024-05-17T18:35:51","modified_gmt":"2024-05-17T18:35:51","slug":"careers","status":"publish","type":"page","link":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/careers\/","title":{"rendered":"Careers"},"content":{"rendered":"\n<p class=\"has-text-align-center\">Please contact Dr. Colin Saldanha with any inquiries regarding Undergraduate or Graduate research positions.<\/p>\n\n\n\n<p class=\"has-text-align-center\">saldanha@american.edu<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Please contact Dr. Colin Saldanha with any inquiries regarding Undergraduate or Graduate research positions. saldanha@american.edu<\/p>\n","protected":false},"author":4248,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-53","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages\/53","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/users\/4248"}],"replies":[{"embeddable":true,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/comments?post=53"}],"version-history":[{"count":0,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages\/53\/revisions"}],"wp:attachment":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/media?parent=53"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}},{"id":52,"date":"2024-05-17T18:35:49","date_gmt":"2024-05-17T18:35:49","guid":{"rendered":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/?page_id=52"},"modified":"2024-05-29T14:39:50","modified_gmt":"2024-05-29T14:39:50","slug":"about-us-2","status":"publish","type":"page","link":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/about-us-2\/","title":{"rendered":"About Us"},"content":{"rendered":"\n<p class=\"has-text-align-left\"><strong>Welcome to the Neuroendocrinology Lab!!!&nbsp;<\/strong><\/p>\n\n\n\n<p>Members of my laboratory and I are curious about the interactions among hormones, the brain, and behavior. More specifically, we study the spatial and temporal precision of hormone provision, and how this precision results in complex behaviors like learning and memory.&nbsp;<\/p>\n\n\n\n<p>Here\u2019s the deal \u2013 some hormones are synthesized in many different tissues, affect many different targets, and modulate many different behaviors. How then, is the right hormone provided to the right target at the right time?&nbsp;&nbsp;<\/p>\n\n\n\n<p>Estrogens, like estradiol (E2) is one such hormone. It is synthesized in the ovary, placenta, adipose tissue, the pituitary, and in the brain itself. E2 can affect parts of the forebrain, midbrain, hindbrain, and the spinal cord to influence behaviors as distinct as balance, mood, energy balance, aggression, memory, and sex. To make things even more interesting, E2 is a steroid (oil soluble, not water soluble), and thus has potential access to every cell in the body (every cell has a fat membrane). So, how can E2 be provided to just the right target tissue at just the right time and at just the right dose, to affect any one particular behavior while excluding effects on others?&nbsp;<\/p>\n\n\n\n<p>Our laboratory studies E2 synthesis in the brains of songbirds. The zebra finch has been a resilient animal model in neuroendocrinology for many reasons, one of which is that these birds make high levels of E2 in many different parts of the brain. This is accomplished by expressing the enzyme aromatase at high levels. Aromatase is the enzyme that converts testosterone to estradiol.&nbsp;&nbsp;<\/p>\n\n\n\n<p><strong>We study two distinct phenomena:&nbsp;<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\" start=\"1\">\n<li>Aromatase expression in presynaptic boutons and postsynaptic dendrites&nbsp;<\/li>\n<\/ol>\n\n\n\n<ol class=\"wp-block-list\" start=\"2\">\n<li>Aromatase expression in astrocytes&nbsp;<\/li>\n<\/ol>\n\n\n\n<p><strong>The Synaptocrine Hypothesis&nbsp;<\/strong><\/p>\n\n\n\n<p>Almost twenty years ago, we located the aromatase protein in presynaptic boutons in the zebra finch brain using immunocytochemistry and electron microscopy (Peterson et al., 2005). We corroborated these results by measuring aromatase activity and expression in synaptosomes (Rohmann et al. 2007). Along with our collaborators we termed this form of signaling, \u201csynaptocrine,\u201d since it is very different from other forms of secreted signaling (Remage-Healey et al., 2011; Saldanha et al., 2011). Since then we have learned that synaptic aromatase may be regulated differently from that in other parts of the neuron (Cornil et al., 2012) and that synaptic aromatase may be a critical modulator of memory function (Bailey et al., 2013; 2017). Current projects explore the interactions among electrical activity, synaptic aromatase and neurotransmitter release.&nbsp;<\/p>\n\n\n\n<p><strong>Induced aromatase in astrocytes&nbsp;<\/strong><\/p>\n\n\n\n<p>Also about twenty years ago, we discovered that injury to the zebra finch brain results in the induction of aromatase expression in a cell type that normally does not express this protein. Astrocytes around the site of brain injury begin transcribing and translating the aromatase gene and transcript within hours of brain damage (Peterson et al., 2001). We now know that this induction of aromatase expression limits the size of brain damage (Wynne &amp; Saldanha, 2004; Saldanha et al., 2005; Wynne et al., 2008) and increases cytogenesis and neurogenesis (Walters &amp; Saldanha, 2008; Walters et al., 2011). Interestingly, it is the inflammation that results from brain trauma that induces aromatase expression in astrocytes (Pedersen et al., 2017) and the E2 synthesized by astrocytes reduces chronic inflammation (Pedersen et al., 2016). Current projects involve understanding the generality of this phenomena in transgenic mice.&nbsp;<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/key-figures\/\">Key Figures<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/publications\/\">Selected Publications<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Welcome to the Neuroendocrinology Lab!!!&nbsp; Members of my laboratory and I are curious about the interactions among hormones, the brain, and behavior. More specifically, we study the spatial and temporal precision of hormone provision, and how this precision results in complex behaviors like learning and memory.&nbsp; Here\u2019s the deal \u2013 some hormones are synthesized in [&hellip;]<\/p>\n","protected":false},"author":4248,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-52","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages\/52","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/users\/4248"}],"replies":[{"embeddable":true,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/comments?post=52"}],"version-history":[{"count":0,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages\/52\/revisions"}],"wp:attachment":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/media?parent=52"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}},{"id":46,"date":"2024-05-17T18:35:49","date_gmt":"2024-05-17T18:35:49","guid":{"rendered":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/?page_id=46"},"modified":"2024-05-29T14:28:57","modified_gmt":"2024-05-29T14:28:57","slug":"carb-smart-science","status":"publish","type":"page","link":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/carb-smart-science\/","title":{"rendered":"Carb Smart Science"},"content":{"rendered":"\n<h4 class=\"wp-block-heading has-text-align-center\">Find all of the low-carb recipes linked below, or on our Instagram page!<\/h4>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"http:\/\/linkin.bio\/carbsmartscience\">Links<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.instagram.com\/carbsmartscience\/\">Instagram<\/a><\/div>\n<\/div>\n\n\n\n<p>Hello all, and welcome to <strong>CarbSmartScience<\/strong>. I am Colin, and this page is an attempt to flood the interwebs with recipes that are healthy and low in carbohydrates.<\/p>\n\n\n\n<p>By way of a brief introduction, I am a Neuroscientist and a Psychologist. I conduct research on how hormones (specifically steroid hormones like estrogen) interact with brain circuits to produce behaviors like learning and memory.<\/p>\n\n\n\n<p>I also have chronic heart disease, and have dealt with this condition through a heart-attack (2008), and with an aortic aneurysm that was diagnosed in 2017. The latter lead directly to major heart surgery to replace the root and part of my ascending aorta. I used to be an athlete through high school and early college, and now have both hips replaced with shiny titanium implants that make me feel quite bionic! Put all this together and perhaps you can see why eating carefully and maintaining a healthy weight is an ongoing preoccupation.<\/p>\n\n\n\n<p>It&#8217;s been over thirteen years that I have managed my weight. I started on The South Beach Diet (February 2011), and have stayed on it since.<\/p>\n\n\n\n<p>This is me in Dec 2007; 41 years old, 6\u20195\u201d, and 270lb, eleven months before my heart attack:<\/p>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"597\" height=\"1024\" data-id=\"47\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2853-597x1024.jpg\" alt=\"\" class=\"wp-image-47\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2853-597x1024.jpg 597w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2853-175x300.jpg 175w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2853-768x1318.jpg 768w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2853.jpg 783w\" sizes=\"(max-width: 597px) 100vw, 597px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"807\" height=\"1024\" data-id=\"48\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2854-807x1024.jpg\" alt=\"\" class=\"wp-image-48\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2854-807x1024.jpg 807w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2854-236x300.jpg 236w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2854-768x975.jpg 768w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2854.jpg 1025w\" sizes=\"(max-width: 807px) 100vw, 807px\" \/><\/figure>\n<\/figure>\n\n\n\n<p>Here\u2019s me 2020 \u2013 now; 57 years old, 6\u20194\u201d (yes \u2013 compression), and 200lb.<\/p>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-2 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"590\" height=\"895\" data-id=\"49\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2856.jpg\" alt=\"\" class=\"wp-image-49\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2856.jpg 590w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2856-198x300.jpg 198w\" sizes=\"(max-width: 590px) 100vw, 590px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"865\" height=\"1024\" data-id=\"50\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2855-865x1024.jpg\" alt=\"\" class=\"wp-image-50\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2855-865x1024.jpg 865w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2855-253x300.jpg 253w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2855-768x909.jpg 768w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2855.jpg 1110w\" sizes=\"(max-width: 865px) 100vw, 865px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"739\" height=\"927\" data-id=\"51\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2857.jpg\" alt=\"\" class=\"wp-image-51\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2857.jpg 739w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/IMG_2857-239x300.jpg 239w\" sizes=\"(max-width: 739px) 100vw, 739px\" \/><\/figure>\n<\/figure>\n\n\n\n<p>I hope you find these recipes useful, informative, and tasty! Please note, all pasta dishes were made with high fiber pasta (FiberGourmet, Chickpea pasta etc). All breads were made with 100% whole wheat flour and not more than one slice per meal.<\/p>\n\n\n\n<p>Thing I miss are: certain breads, pasta, potatoes, beer!<\/p>\n\n\n\n<p>Things I gain are: my life, my family, my friends, and my students.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Find all of the low-carb recipes linked below, or on our Instagram page! Hello all, and welcome to CarbSmartScience. I am Colin, and this page is an attempt to flood the interwebs with recipes that are healthy and low in carbohydrates. By way of a brief introduction, I am a Neuroscientist and a Psychologist. I [&hellip;]<\/p>\n","protected":false},"author":4248,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-46","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages\/46","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/users\/4248"}],"replies":[{"embeddable":true,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/comments?post=46"}],"version-history":[{"count":0,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages\/46\/revisions"}],"wp:attachment":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/media?parent=46"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}},{"id":26,"date":"2024-05-17T18:35:49","date_gmt":"2024-05-17T18:35:49","guid":{"rendered":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/?page_id=26"},"modified":"2024-05-29T14:19:38","modified_gmt":"2024-05-29T14:19:38","slug":"about-us","status":"publish","type":"page","link":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/about-us\/","title":{"rendered":"Our Team"},"content":{"rendered":"\n<h3 class=\"wp-block-heading has-text-align-center\">Principal Investigator<\/h3>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"754\" height=\"754\" src=\"http:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/2020-Colin-Home-Office-1.jpg\" alt=\"\" class=\"wp-image-60\" style=\"width:238px;height:auto\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/2020-Colin-Home-Office-1.jpg 754w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/2020-Colin-Home-Office-1-300x300.jpg 300w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/2020-Colin-Home-Office-1-150x150.jpg 150w\" sizes=\"(max-width: 754px) 100vw, 754px\" \/><figcaption class=\"wp-element-caption\">Colin Saldanha, PhD. Professor of Neuroscience at American University<\/figcaption><\/figure>\n\n\n\n<h3 class=\"wp-block-heading has-text-align-center\">Current Team<\/h3>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-3 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"960\" data-id=\"68\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/thumbnail_240404_American_University_8320c-X2_edited.jpg\" alt=\"\" class=\"wp-image-68\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/thumbnail_240404_American_University_8320c-X2_edited.jpg 768w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/thumbnail_240404_American_University_8320c-X2_edited-240x300.jpg 240w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/><figcaption class=\"wp-element-caption\">Clementine Harvey, 2nd Year PhD Student<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"574\" height=\"650\" data-id=\"61\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Rebecca-Andrade.jpg\" alt=\"\" class=\"wp-image-61\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Rebecca-Andrade.jpg 574w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Rebecca-Andrade-265x300.jpg 265w\" sizes=\"(max-width: 574px) 100vw, 574px\" \/><figcaption class=\"wp-element-caption\">Rebecca Andrade, 2nd Year PhD Student<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1449\" height=\"1891\" data-id=\"65\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/7P7A7152-copy-1-edited.jpg\" alt=\"\" class=\"wp-image-65\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/7P7A7152-copy-1-edited.jpg 1449w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/7P7A7152-copy-1-edited-230x300.jpg 230w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/7P7A7152-copy-1-edited-785x1024.jpg 785w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/7P7A7152-copy-1-edited-768x1002.jpg 768w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/7P7A7152-copy-1-edited-1177x1536.jpg 1177w\" sizes=\"(max-width: 1449px) 100vw, 1449px\" \/><figcaption class=\"wp-element-caption\">Abby St. Jean, 3rd Year Undergraduate<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"881\" height=\"1024\" data-id=\"64\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Yvette-Nau-1-881x1024.jpeg\" alt=\"\" class=\"wp-image-64\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Yvette-Nau-1-881x1024.jpeg 881w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Yvette-Nau-1-258x300.jpeg 258w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Yvette-Nau-1-768x893.jpeg 768w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Yvette-Nau-1-1321x1536.jpeg 1321w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Yvette-Nau-1-1762x2048.jpeg 1762w\" sizes=\"(max-width: 881px) 100vw, 881px\" \/><figcaption class=\"wp-element-caption\">Yvette Nau, 3rd Year Undergraduate<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1434\" height=\"1911\" data-id=\"66\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/EllieBashaw-edited-1.jpg\" alt=\"\" class=\"wp-image-66\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/EllieBashaw-edited-1.jpg 1434w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/EllieBashaw-edited-1-225x300.jpg 225w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/EllieBashaw-edited-1-768x1023.jpg 768w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/EllieBashaw-edited-1-1153x1536.jpg 1153w\" sizes=\"(max-width: 1434px) 100vw, 1434px\" \/><figcaption class=\"wp-element-caption\">Ellie Bashaw, 3rd Year Undergraduate<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"483\" height=\"493\" data-id=\"67\" src=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Ellie-Pryor.jpg\" alt=\"\" class=\"wp-image-67\" srcset=\"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Ellie-Pryor.jpg 483w, https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-content\/uploads\/sites\/2410\/2024\/05\/Ellie-Pryor-294x300.jpg 294w\" sizes=\"(max-width: 483px) 100vw, 483px\" \/><figcaption class=\"wp-element-caption\">Ellie Pryor, 2nd Year Undergraduate<\/figcaption><\/figure>\n<\/figure>\n\n\n\n<h3 class=\"wp-block-heading has-text-align-center\">Alumni<\/h3>\n\n\n\n<p>Jo Spurgeon, B.S. Neuroscience, American University &#8217;24<\/p>\n\n\n\n<p>Zoe Joy, B.S. Neuroscience, American University &#8217;23<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Principal Investigator Current Team Alumni Jo Spurgeon, B.S. Neuroscience, American University &#8217;24 Zoe Joy, B.S. Neuroscience, American University &#8217;23<\/p>\n","protected":false},"author":4248,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-26","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages\/26","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/users\/4248"}],"replies":[{"embeddable":true,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/comments?post=26"}],"version-history":[{"count":0,"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/pages\/26\/revisions"}],"wp:attachment":[{"href":"https:\/\/edspace.american.edu\/labofneuroendocrinology\/wp-json\/wp\/v2\/media?parent=26"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}]