UCLA Miniscope Project

Daniel Aharoni of the Golshani, Silva, and Khakh Lab at UCLA has shared the following about Miniscope:


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This open source miniature fluorescence microscope uses wide-field fluorescence imaging to record neural activity in awake, freely behaving mice. The Miniscope has a mass of 3 grams and uses a single, flexible coaxial cable (0.3mm to 1.5mm diameter) to carry power, control signals, and imaging data to open source Data Acquisition (DAQ) hardware and software. Miniscope.org provides a centralized location for sharing design files, source code, and other relevant information so that a community of users can share ideas and developments related to this important imaging technique. Our goal is to help disseminate this technology to the larger neuroscience community and build a foundation of users that will continue advancing this technology and contribute back to the project. While the Miniscope system described here is not an off-the-shelf commercial solution, we have focused on making it as easy as possible for the average neuroscience lab to build and modify, requiring minimal soldering and hands on assembly.
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Video demonstrating GCamp6F imaging in CA1 using the UCLA Miniscope

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