DIY-NAMIC

September 10, 2020 Katherine Nautiyal from Dartmouth College has kindly shared the following about DIY-NAMIC, a high-throughput method to measure complex phenotypes in the homecage. ‘Operant behavioral paradigms provide rich data sets which are very useful for assessing manipulations in rodents models for neuropsychiatric disorders. However, the behavioral testing generally requires daily training for many […]

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NINscope: a versatile miniscope for multi-region circuit investigations

September 3, 2020 Andres de Groot and colleagues from the Netherlands Institute for Neuroscience have created a lightweight, versatile miniscope for fluorescence imaging and optogenetic stimulation. Miniaturized fluorescent microscopes (miniscopes) are powerful tools used for the monitoring of neural signals during unrestrained behavior. NINscope is a compact miniscope that has an integrated inertial measurement sensor […]

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Tetroplater

August 27, 2020 Jumpei Matsumoto from the University of Toyama has generously shared the following about Tetroplater, an open-source circuit for microwire tetrode gold plating. “Gold plating is necessary/effective for microwire tetrodes for recording neuronal activity. For the gold plating, the electrode tip is electroplated with current pulses, until the impedance reaches to the target […]

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An Open Source Syringe Pump Controller for Fluid Delivery of Multiple Volumes

August 20, 2020 Linda Amarante and colleagues from American University have developed and shared an open-source syringe pump controller for dispensing precise volumes of fluid over precise timescales. Delivering rewards are a crucial part of behavioral neuroscience experiments. In the case of liquid rewards, such as water, juice, chocolate milk or sucrose solutions, syringe pumps […]

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An Open Source Automated Bar Test for Measuring Catalepsy in Rats

August 6, 2020 Researchers at the University of Guelph have created a low-cost automated apparatus for measuring catalepsy that increases measurement accuracy and reduces observer bias. Catalepsy is a measure of muscular rigidity that can result from several factors including Parkinson’s disease, or pharmacological exposure to antipsychotics or cannabis. Catalepsy bar tests are widely used […]

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DeepFly3D, a deep learning-based approach for 3D limb and appendage tracking in tethered, adult Drosophila

July 23, 2020 Semih Günel and colleagues have created a deep learning-based pose estimator for studying how neural circuits control limbed behaviors in tethered Drosophila. Appendage tracking is an important behavioral measure in motor circuit research. Up until now, algorithms for accurate 3D pose estimation in small animals such as Drosophila did not exist. Rather, […]

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BonVision

July 16, 2020 In a recent bioRxiv preprint, Gonçalo Lopes and colleagues from NeuroGEARS and University College London have shared information about BonVision — an open source software for creating and controlling visual environments. With advances in computer gaming and software rendering, it is now possible to create realistic virtual environments. These virtual environments, which […]

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MNE Scan: Software for real-time processing of electrophysiological data

July 9, 2020 In a 2018 Journal of Neuroscience Methods article, Lorenz Esch and colleagues present MNE Scan, a software that provides real-time acquisition and processing of electrophysiological data. MNE Scan is a state-of-the-art real-time processing software for clinical MEG and EEG data. By allowing for real-time analysis of neuronal activity, MNE Scan enables the […]

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