CHEndoscope

Jul 2, 2018

In Current Protocols in Neuroscience, Alexander Jacob and colleagues share their open source compact head-mounted endoscope (CHEndoscope) for imaging in the awake behaving mouse.


This miniature microscope device is designed to provide an accessible set of calcium imaging tools to investigate the relationship between behavior and population neuronal activity for in vivo rodents. The CHEndoscope is open source, flexible, and consists of only 4 plastic components that can be 3D printed. It uses an implanted gradient index (GRIN) lens in conjunction with the genetically encoded calcium indicator GCaMP6 to image calcium transients from hundreds of neurons simultaneously in awake behaving mice. The aim of the open source model is to provide an accessible and flexible set of calcium imaging tools for the neuroscience research community. The linked article describes in depth the assembly, surgical implantation, data collection, and processing of calcium signals using the CHEndoscope. 

 This research tool was created by your colleagues. Please acknowledge the Principal Investigator, cite the article in which the tool was described, and include an RRID in the Materials and Methods of your future publications.  Project portal RRID:SCR_021587; Software RRID:SCR_021616

 

Check out projects similar to this!

Miniscope-LFOV

Miniscope-LFOV

E-Scope

E-Scope

FARESHARE

FARESHARE

custom-fitting cranial implants

custom-fitting cranial implants

LFP Monitoring: Multianimal Chronic Video Platform for Behavioral Scoring

LFP Monitoring: Multianimal Chronic Video Platform for Behavioral Scoring

BrainWAVE: Noninvasive Rhythm Stimulation

BrainWAVE: Noninvasive Rhythm Stimulation

Application of 3D Printing Technology to Produce Hippocampal Customized Guide Cannulas

Application of 3D Printing Technology to Produce Hippocampal Customized Guide Cannulas

RIVETS

RIVETS

OpBox

OpBox

Falcon: a highly flexible open-source software for closed-loop neuroscience

Falcon: a highly flexible open-source software for closed-loop neuroscience

Have questions? Send us an email!